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Vaccination: Meningitis Vaccine

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Total 5481 results found since Jan 2013.

Clinical and Laboratory Findings of 12 Children with Invasive Meningococcal Disease in Pediatric Intensive Care Unit
CONCLUSION: Mortality related to IMD is higher among children with severe meningococcemia despite early interventions in PICU. Routine use of meningococcal vaccines during childhood would be a better strategy for controlling IMD in both developing and developed countries.PMID:34527377 | PMC:PMC8435381 | DOI:10.1155/2021/9713918
Source: Critical Care Research and Practice - September 16, 2021 Category: Intensive Care Authors: Eylem Kiral Ayse Filiz Yetimakman Source Type: research

Epidemiology of Community-Onset Severe Bacterial Infections in Children and Its Evolution: A Population-Based Study in France*
Conclusions: The incidence and mortality rate of community-onset severe bacterial infections, except for S. aureus infection, have decreased in France. N. meningitidis and S. pneumoniae continue to account for many infections, which indicates the need for better vaccination coverage and spectrum.
Source: Pediatric Critical Care Medicine - June 1, 2020 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Hospitals With the Highest Intensive Care Utilization Provide Lower Quality Pneumonia Care to the Elderly*
Objective: Quality of care for patients admitted with pneumonia varies across hospitals, but causes of this variation are poorly understood. Whether hospitals with high ICU utilization for patients with pneumonia provide better quality care is unknown. We sought to investigate the relationship between a hospital’s ICU admission rate for elderly patients with pneumonia and the quality of care it provided to patients with pneumonia. Design: Retrospective cohort study. Setting: Two thousand eight hundred twelve U.S. hospitals. Patients: Elderly (age ≥ 65 years) fee-for-service Medicare beneficiaries with either a (1) prin...
Source: Critical Care Medicine - May 16, 2015 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Controlled Human Infection and Re-Challenge with Streptococcus Pneumoniae Reveals the Protective Efficacy of Carriage in Healthy Adults.
CONCLUSIONS: Experimental human carriage resulted in mucosal and systemic immunological responses that conferred protection against re-colonization and invasive pneumococcal disease. These data suggest that mucosal pneumococcal vaccination strategies maybe important for vulnerable patient groups, particularly the elderly, who do not sustain carriage. PMID: 23370916 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - January 31, 2013 Category: Respiratory Medicine Authors: Ferreira DM, Neill DR, Bangert M, Gritzfeld JF, Green N, Wright AK, Pennington SH, Moreno LB, Moreno AT, Miyaji EN, Wright AD, Collins AM, Goldblatt D, Kadioglu A, Gordon SB Tags: Am J Respir Crit Care Med Source Type: research

First Human Challenge Testing of a Pneumococcal Vaccine - Double Blind Randomised Controlled Trial.
CONCLUSIONS: PCV reduced pneumococcal colonisation rate, density and duration in healthy adults. The experimental human pneumococcal colonisation model is a safe, cost-effective and efficient method to determine the protective efficacy of new vaccines on pneumococcal colonisation; PCV provides a 'gold standard' against which to test these novel vaccines. Clinical trial registration available at www.isrctn.com, ID 45340436. PMID: 26114410 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - June 26, 2015 Category: Respiratory Medicine Authors: Collins AM, Wright AD, Mitsi E, Gritzfeld JF, Hancock CA, Pennington SH, Wang D, Morton B, Ferreira DM, Gordon SB Tags: Am J Respir Crit Care Med Source Type: research